IMIS - Marine Research Groups | Compendium Coast and Sea

IMIS - Marine Research Groups

[ report an error in this record ]basket (1): add | show Print this page

one publication added to basket [30178]
Modulatory effects of adenosine on Porichthys luminescence
Mallefet, J.; Baguet, F.; Fauville, C. (1993). Modulatory effects of adenosine on Porichthys luminescence. J. Exp. Zool. 266(1): 1-10
In: The Journal of Experimental Zoology. Wiley Interscience: New York, etc.. ISSN 0022-104X; e-ISSN 1097-010X, more
Peer reviewed article  

Available in  Authors 

Keyword
    Marine/Coastal

Authors  Top 
  • Mallefet, J., more
  • Baguet, F., more
  • Fauville, C.

Abstract
    The modulatory effects of exogenous applications of adenosine on luminous organs (photophores) of the fish Porichthys were studied. Pretreatment of photophores with adenosine (10-7 to 10-3 M) potentiated both phases of adrenaline induced luminescence. The first peak of light (Lmax1) showed a 3-fold increase following 10-7 M adenosine treatment; a maximal increase of 12-fold was observed with 10-3 M adenosine. The second peak of light (Lmax2) exhibited a similar dose-response curve, but the maximal increase was attained with 10-4 M adenosine. The potentiating effect of 1 muM adenosine on light emission triggered by adrenaline increased for adrenaline concentrations ranging from 10-7 to 10-4 M for Lmax1, but it remained stable for Lmax2. All 4 P1-purinergic agonists tested at the final concentration of 10-4 M induced a potentiation of adrenaline luminescence with the following rank of potency: L-PIA > NECA > CADO greater-than-or-equal-to CHA = ADO for Lmax1 and NECA > CADO > ADO > CHA > L-PIA for Lmax2. The potentiating effect of adenosine was antagonized with the following rank of potency by the P-1 purinergic antagonists: CPT > DPMX greater-than-or-equal-to AMINO > THEO for Lmax1 and CPT > AMINO > THEO greater-than-or-equal-to DPMX for Lmax2. According to the classification of purinergic receptors, our results suggest that P1-purinergic receptors might be implicated in the adenosine potentiation of Porichthys adrenaline luminescence. Experiments also showed that noradrenaline luminescence is inhibited by 1 µM adenosine pretreatment. Further work will be necessary to elucidate the mechanism involved in the modulatory roles played by the purinergic receptors on adrenaline and noradrenaline luminescence in Porichthys photophores.

All data in the Integrated Marine Information System (IMIS) is subject to the VLIZ privacy policy Top | Authors