Engineering E. coli to have a hybrid Archaeal/Bacterial membrane
Villanueva, L. (2018). Engineering E. coli to have a hybrid Archaeal/Bacterial membrane. Trends microbiol. (Regul. ed.) 26(7): 559-560. https://dx.doi.org/10.1016/j.tim.2018.05.003
In: Trends in Microbiology. Elsevier: Cambridge. ISSN 0966-842X; e-ISSN 1878-4380, meer
Bacteria and Archaea have membrane lipids with an opposite stereochemistry. The most plausible explanation for this differentiation implies an unstable heterochiral membrane stage. A recent study engineered Escherichia coli with a significant abundance of archaeal lipids showing higher robustness, disproving heterochirality as the driving force for this differentiation.
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